Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IQGAP2 All Species: 31.82
Human Site: S24 Identified Species: 77.78
UniProt: Q13576 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13576 NP_006624.2 1575 180578 S24 I V D D E R L S A E E M D E R
Chimpanzee Pan troglodytes XP_001146396 1575 180717 S24 I V D D E R L S A E E M D E R
Rhesus Macaque Macaca mulatta XP_001114017 1632 184597 Q24 T A E E M D E Q R R Q N V A Y
Dog Lupus familis XP_536318 1641 188145 S90 I V D D E R L S A E E M D E R
Cat Felis silvestris
Mouse Mus musculus Q3UQ44 1575 180509 S24 I V D D E R L S A E E M D E R
Rat Rattus norvegicus NP_001101959 1657 188814 T27 V L D N E R L T A E E M D E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413959 2023 228609 T391 V L D N E R L T A E E M D E R
Frog Xenopus laevis NP_001082588 1660 189688 S24 I V D D E R L S A E E M D E R
Zebra Danio Brachydanio rerio NP_001121812 1680 191619 S36 I V D D E R L S A E E M D E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203784 771 87814
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 50.3 86.7 N.A. 88.9 58.2 N.A. N.A. 48.7 66.6 61.4 N.A. N.A. N.A. N.A. 25.2
Protein Similarity: 100 99.8 69 91.5 N.A. 95.3 74.7 N.A. N.A. 61.5 78 75.8 N.A. N.A. N.A. N.A. 38.3
P-Site Identity: 100 100 0 100 N.A. 100 73.3 N.A. N.A. 73.3 100 100 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 80 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 80 60 0 10 0 0 0 0 0 0 80 0 0 % D
% Glu: 0 0 10 10 80 0 10 0 0 80 80 0 0 80 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 20 0 0 0 0 80 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 80 0 0 0 % M
% Asn: 0 0 0 20 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 80 0 0 10 10 0 0 0 0 80 % R
% Ser: 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 % S
% Thr: 10 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % T
% Val: 20 60 0 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _